How Does Invokana Cause Ketoacidosis?


In May 2015, the Food and Drug Administration (FDA) has warned that a new class of Type 2 diabetes drugs, including Johnson & Johnson’s blockbuster Invokana, may cause a serious condition called ketoacidosis. Many patients experiencing this condition took the drug for about 2 weeks before symptoms showed up.

Invokana causes a diabetic’s blood sugar to leave his or her body through urine and is among the most popular SGLT2 inhibitors, a class of Type 2 diabetes drugs. The drug can cause a condition called ketoacidosis that happens when the body produces too many acids called ketones.

Diabetic ketoacidosis (DKA) is a life-threatening condition that comes about when cells cannot get the glucose they need due to a lack of insulin. Instead, the body breaks down fat and muscle for energy. When this happens, fatty acids (ketones) are produced and cause a chemical imbalance called diabetic ketoacidosis.

Ketoacidosis Symptoms

  • Abdominal pain
  • Confusion
  • Difficulty breathing
  • Dizziness or fainting
  • Fruity breath
  • Increased thirst
  • Increased urination
  • Nausea
  • Unconsciousness
  • Unusual fatigue or sleepiness.
  • Vomiting
  • Weakness

A very similar medication that may cause the same dangerous side effects is Invokamet. J&J also combines the active ingredient in Invokana with metformin and markets it as Invokamet.

J&J and its Janssen Pharmaceuticals unit made $278 million on Invokana in the first quarter of 2015 alone. With more people being diagnosed with Type 2 diabetes than ever before, many expect that claims of ketoacidosis and other serious side effects will only continue to grow.

Raizner Slania Accepting Invokana Ketoacidosis Cases

Injuries caused by an antidiabetic medication may require hospitalization and long-term medical care.  Patients who are injured by medications may be eligible for financial compensation for medical expenses, lost wages, and more. Loved ones of patients who die due to drug injury may be eligible to file a wrongful death lawsuit. If you developed Ketoacidosis after taking Invokana or another type 2 diabetes drug, you may have legal options. Contact us today.

Sharing is caring!